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Furthermore, recent evidence on the effects of exogenous melatonin on sleep and circadian disorders was integrated in psychiatric disorders such as autism spectrum disorder, attention deficit hyperactivity disorder, neurocognitive disorder, schizophrenia, bipolar disorder, depression, anxiety, and eating disorder (Table 2)

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( A ) SA--gal assay showing that FOXO4-DRI treatment decreases SA--gal activity in the testicular interstitium in aged mice